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- I’m a Virus (music video)
- Virus Interactive Tutorial (AP Biology Level)
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I’m a Virus (Lyrics)
[qwiz]
[h]Virus Interactive Lyrics
[q labels = “top”]
I’m a virus, an _________ particle,
a nano-thug, a pirate, the genuine article
Ebola, chickenpox, west Nile, influenza,
Yellow fever, AIDS, herpes, SARS, I’m comin’ right at ya
I’m not a _____, not an independent organism,
I don’t even have my own __________,
I only __________ myself by taking over cells,
Then I bust ‘em apart, no wonder you don’t feel well!
[l]cell
[fx] No. Please try again.
[f*] Correct!
[l]infectious
[fx] No. Please try again.
[f*] Excellent!
[l]metabolism
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]reproduce
[fx] No, that’s not correct. Please try again.
[f*] Good!
[q labels = “top”]
My structure is simple, mostly ________ and genes,
Packaged as a sub-micron killing machine,
My ________ made of capsomeres that self _________,
Whenever cells see me they start to tremble,
Inside my capsid is where my ______ reside,
I got DNA or _____ on the inside,
And the rest of me is various proteins whose role,
Is assisting in assaulting cells and taking control.
CHORUS
I’m a virus,
Gonna use your cells to ________ me
I’m a virus
The death of your cells is the life of me
[l]assemble
[fx] No. Please try again.
[f*] Excellent!
[l]capsid’s
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]genes
[fx] No, that’s not correct. Please try again.
[f*] Good!
[l]proteins
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]replicate
[fx] No. Please try again.
[f*] Excellent!
[l]RNA
[fx] No, that’s not correct. Please try again.
[f*] Great!
[q labels = “top”]
The _____ cycle shows one method of attack,
I attach to the cell surface, and pierce it like a tack
Inject my ______ inside, use my victim’s __________,
to make my genes and proteins for reproducing more of me.
Step 1, __________ grab the membrane or the wall
2: inject my genes, this cell is gonna fall.
3: use the victim’s __________ and ribosomes,
To synthesize my proteins and replicate my genome.
4: tail piece and capsid self assembly,
5: I’m all together now, look at all my progeny
6 is lysis, I burst that _____ apart,
Now I’m looking for more victims I can dearly depart.
CHORUS
[l]cell
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]genes
[fx] No. Please try again.
[f*] Great!
[l]lytic
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]machinery
[fx] No, that’s not correct. Please try again.
[f*] Great!
[l]polymerase
[fx] No, that’s not correct. Please try again.
[f*] Great!
[l]tail fibers
[fx] No, that’s not correct. Please try again.
[f*] Great!
[q labels = “top”]
Sometimes instead of lysing I __________
Which happens after I inject my genes inside
I slip into your ___________ a thief inside your room
A menacing and silent presence bringer of doom
Integrated in you, your ______ my home,
And see what happens when you replicate your chromosomes
Each copy that you copy copies me as well as you,
You might make a million ______, there’s nothin’ you can do
[l]chromosome
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]copies
[fx] No. Please try again.
[f*] Correct!
[l]DNA’s
[fx] No, that’s not correct. Please try again.
[f*] Good!
[l]lysogenize
[fx] No. Please try again.
[f*] Correct!
[q labels = “top”]
My lurking hiding being’s called a _________ or provirus,
And if you got another name just call us or wire us,
Or write it on papyrus ‘til the moment that I emerge,
from your DNA I’m _____ now a cell destroying scourge.
And suddenly your cells are _____ watch me as I lyse them,
I’m a pirate so forget your plans my program now denies them,
Your cells are _____ factories they’re making millions more of me
I leave your cells and now I’m free Infecting you’s my destiny
CHORUS
[l]dying
[fx] No. Please try again.
[f*] Good!
[l]lytic
[fx] No, that’s not correct. Please try again.
[f*] Correct!
[l]prophage
[fx] No. Please try again.
[f*] Excellent!
[l]virus
[fx] No. Please try again.
[f*] Great!
[q labels = “top”]
Now meet my associate the virus ______
Who’s helpless target is the cell called “T”
HIV causes ________________,
Raising cancer and infection vulnerability
Remember that the T’s an essential cell
In the _______ system army it’s the general
So knocking out the ______ sets the stage
For cancers, germs and viruses like me to invade!
[l]HIV
[fx] No. Please try again.
[f*] Great!
[l]immune
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]immunodeficiency
[fx] No. Please try again.
[f*] Great!
[l]T-cell
[fx] No. Please try again.
[f*] Good!
[q labels = “top”]
HIV’s genes are made of _____,
Outside its capsid’s a ___________ membrane,
A skin stolen from the cell it last dispatched,
studded with proteins that let it attach,
To a protein on the _____ called CD4
Inducing that cell to open up its door,
Inviting in _____ enzymes and core,
That T-cells already done for.
[l]HIV’s
[fx] No, that’s not correct. Please try again.
[f*] Good!
[l]phospholipid
[fx] No, that’s not correct. Please try again.
[f*] Correct!
[l]RNA
[fx] No, that’s not correct. Please try again.
[f*] Correct!
[l]T-cell
[fx] No. Please try again.
[f*] Excellent!
[q labels = “top”]
HIV’s a __________ it’s next routine,
has to do with transforming its RNA genes
___________________ takes its RNA
And reverse transcribes it into _____
Then this DNA integrates into your ______________,
Like a __________ prophage in your genome.
This proviral DNA’s __________ and translated
As new virus genes and proteins get created
And like any virus all those parts will self _________,
Into new viruses which of course resemble,
the original particle which started the infection,
Acquired by sex, or a needle injection
[l]assemble
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]chromosomes
[fx] No, that’s not correct. Please try again.
[f*] Correct!
[l]DNA
[fx] No, that’s not correct. Please try again.
[f*] Correct!
[l]lysogenic
[fx] No, that’s not correct. Please try again.
[f*] Good!
[l]retrovirus
[fx] No, that’s not correct. Please try again.
[f*] Excellent!
[l]reverse transcriptase
[fx] No, that’s not correct. Please try again.
[f*] Correct!
[l]transcribed
[fx] No, that’s not correct. Please try again.
[f*] Great!
[/qwiz]
2. Interactive Diagrams
(coming soon!)
3. Flashcards, Set 1
[qdeck]
[h]I’m a Virus Flashcards Set 1
[!!!!] +++card 1+++[/!!!]
[q]_______ are best described as infectious particles.
[textentry]
[a]Viruses are best described as infectious particles.
[!!!!] +++card 3+++[/!!!]
[q]Viruses are best described as infectious _________.
[textentry]
[a]Viruses are best described as infectious particles.
[!!!!] +++card 5+++[/!!!]
[q]Viruses can only _______ themselves by taking over cells.
[textentry]
[a]Viruses can only reproduce themselves by taking over cells.
[!!!!] +++card 7+++[/!!!]
[q]At a minimum, viruses consist of _________ surrounded by a protein coat.
[textentry]
[a]At a minimum, viruses consist of genes surrounded by a protein coat.
[!!!!] +++card 9+++[/!!!]
[q]A virus’s outer coat of protein is also known as a ________.
[textentry]
[a]A virus’s outer coat of protein is also known as a capsid.
[!!!!] +++card 11+++ [/!!!]
[q]The capsid is made of capsomeres that self-________.
[textentry]
[a]The capsid is made of capsomeres that self-assemble.
[!!!!] +++card 13+++ [/!!!]
[q]Viral genes can consist of ________ or RNA.
[textentry]
[a]Viral genes can consist of DNA or RNA.
[!!!!] +++card 15+++ [/!!!]
[q]In the ________ cycle, viruses take over cells, use them to make more viruses, and destroy them as new viruses burst out of the infected cell.
[textentry]
[a]In the lytic cycle, viruses take over cells, use them to make more viruses, and destroy them as new viruses burst out of the infected cell.
[!!!!] +++card 17+++ [/!!!]
[q]In the lytic cycle, viruses take over cells, use them to make more viruses, and destroy them as new viruses ______ out of the infected cell.
[textentry]
[a]In the lytic cycle, viruses take over cells, use them to make more viruses, and destroy them as new viruses burst out of the infected cell.
[!!!!] +++card 19+++ [/!!!]
[q]During the lytic cycle, viruses use the cell’s DNA _____ to make viral DNA, and use the cell’s ribosomes to make viral protein.
[textentry]
[a]During the lytic cycle, viruses use the cell’s DNA polymerase to make viral DNA, and use the cell’s ribosomes to make viral protein.
[!!!!] +++card 21+++ [/!!!]
[q]During the lytic cycle, viruses use the cell’s DNA polymerase to make viral DNA, and use the cell’s ribosomes to make viral _____.
[textentry]
[a]During the lytic cycle, viruses use the cell’s DNA polymerase to make viral DNA, and use the cell’s ribosomes to make viral protein.
[!!!!] +++card 23+++ [/!!!]
[q]The lytic cycle begins with the virus attaching to its host cell. It continues with _____ of viral genes into the cell.
[textentry]
[a]The lytic cycle begins with the virus attaching to its host cell. It continues with injection of viral genes into the cell.
[!!!!] +++card 25+++ [/!!!]
[q]The lytic cycle ends with _____: the bursting apart of the host cell as viral progeny are released.
[textentry]
[a]The lytic cycle ends with lysis: the bursting apart of the host cell as viral progeny are released.
[!!!!] +++card 27+++ [/!!!]
[q]The lytic cycle ends with lysis: the bursting apart of the host cell as viral _____ are released.
[textentry]
[a]The lytic cycle ends with lysis: the bursting apart of the host cell as viral progeny are released.
[!!!!] +++card 29+++ [/!!!]
[q]In the lysogenic cycle, viral _____ are incorporated into the host cell’s chromosomes.
[textentry]
[a]In the lysogenic cycle, viral genes are incorporated into the host cell’s chromosomes.
[!!!!] +++card 31+++ [/!!!]
[q]In viruses that attack _____, the viral genes that have integrated themselves into the host’s chromosome are known as a prophage.
[textentry]
[a]In viruses that attack bacteria, the viral genes that have integrated themselves into the host’s chromosome are known as a prophage.
[!!!!] +++card 33+++ [/!!!]
[q]In viruses that attack bacteria, the viral genes that have integrated themselves into the host’s chromosome are known as a _____.
[textentry]
[a]In viruses that attack bacteria, the viral genes that have integrated themselves into the host’s chromosome are known as a prophage.
[!!!!] +++card 35+++ [/!!!]
[q]In viruses that attack eukaryotes, the viral genes that have _____ themselves into the host’s chromosome are known as a provirus.
[textentry]
[a]In viruses that attack eukaryotes, the viral genes that have integrated themselves into the host’s chromosome are known as a provirus.
[!!!!] +++card 37+++ [/!!!]
[q]The target of HIV is the _____.
[textentry]
[a]The target of HIV is the helper-T-cell.
[!!!!] +++card 39+++ [/!!!]
[q]_____ raises an individual’s vulnerability to cancer and infection.
[textentry]
[a]Immunodeficiency raises an individual’s vulnerability to cancer and infection.
[!!!!] +++card 41+++ [/!!!]
[q]Immunodeficiency raises an individual’s vulnerability to cancer and _____.
[textentry]
[a]Immunodeficiency raises an individual’s vulnerability to cancer and infection.
[!!!!] +++card 43+++ [/!!!]
[q]Outside HIV’s capsid is a _____ membrane, derived from its last victim.
[textentry]
[a]Outside HIV’s capsid is a phospholipid membrane, derived from its last victim.
[!!!!] +++card 45+++ [/!!!]
[q]HIV binds with a _____ protein called CD4.
[textentry]
[a]HIV binds with a membrane protein called CD4.
[!!!!] +++card 47+++ [/!!!]
[q]Binding with _____ causes a T cell’s membrane to open and allow in HIV’s enzymes and genes.
[textentry]
[a]Binding with CD4 causes a T cell’s membrane to open and allow in HIV’s enzymes and genes.
[!!!!] +++card 49+++ [/!!!]
[q]Binding with CD4 causes a T cell’s membrane to open and allow in HIV’s _____ and genes.
[textentry]
[a]Binding with CD4 causes a T cell’s membrane to open and allow in HIV’s enzymes and genes.
[!!!!] +++card 51+++ [/!!!]
[q]The enzyme _____ transcribes HIV’s RNA into DNA. That makes HIV a retrovirus.
[textentry]
[a]The enzyme reverse transcriptase transcribes HIV’s RNA into DNA. That makes HIV a retrovirus.
[!!!!] +++card 53+++ [/!!!]
[q]The enzyme reverse transcriptase transcribes HIV’s RNA into _____. That makes HIV a retrovirus.
[textentry]
[a]The enzyme reverse transcriptase transcribes HIV’s RNA into DNA. That makes HIV a retrovirus.
[!!!!] +++card 55+++ [/!!!]
[q]After being converted into DNA, HIV’s genes _____ themselves into the T cell’s chromosomes.
[textentry]
[a]After being converted into DNA, HIV’s genes integrate themselves into the T cell’s chromosomes.
[/qdeck]
4. Flashcards, Set 2
[qdeck]
[h]I’m a Virus Flashcards Set 2
[!!!!] +++card 2+++[/!!!]
[q]Viruses are best described as _________ particles.
[textentry]
[a]Viruses are best described as infectious particles.
[!!!!] +++card 4+++[/!!!]
[q]Unlike cells, viruses lack an independent __________.
[textentry]
[a]Unlike cells, viruses lack an independent metabolism.
[!!!!] +++card 6+++[/!!!]
[q]Viruses can only reproduce themselves by taking over _______.
[textentry]
[a]Viruses can only reproduce themselves by taking over cells.
[!!!!] +++card 8+++[/!!!]
[q]At a minimum, viruses consist of genes surrounded by a protein ______.
[textentry]
[a]At a minimum, viruses consist of genes surrounded by a protein coat.
[!!!!] +++card 10+++ [/!!!]
[q]The capsid is made of __________ that self-assemble.
[textentry]
[a]The capsid is made of capsomeres that self-assemble.
[!!!!] +++card 12+++ [/!!!]
[q]Viral ________ can consist of DNA or RNA.
[textentry]
[a]Viral genes can consist of DNA or RNA.
[!!!!] +++card 14+++ [/!!!]
[q]Viral genes can consist of DNA or _______.
[textentry]
[a]Viral genes can consist of DNA or RNA.
[!!!!] +++card 16+++ [/!!!]
[q]In the lytic cycle, viruses take over cells, use them to make more ________ and destroy them as new viruses burst out of the infected cell.
[textentry]
[a]In the lytic cycle, viruses take over cells, use them to make more viruses, and destroy them as new viruses burst out of the infected cell.
[!!!!] +++card 18+++ [/!!!]
[q]During the _____ cycle, viruses use the cell’s DNA polymerase to make viral DNA, and use the cell’s ribosomes to make viral protein.
[textentry]
[a]During the lytic cycle, viruses use the cell’s DNA polymerase to make viral DNA, and use the cell’s ribosomes to make viral protein.
[!!!!] +++card 20+++ [/!!!]
[q]During the lytic cycle, viruses use the cell’s DNA polymerase to make viral DNA, and use the cell’s _____ to make viral protein.
[textentry]
[a]During the lytic cycle, viruses use the cell’s DNA polymerase to make viral DNA, and use the cell’s ribosomes to make viral protein.
[!!!!] +++card 22+++ [/!!!]
[q]The lytic cycle begins with the virus _____ to its host cell. It continues with injection of viral genes into the cell.
[textentry]
[a]The lytic cycle begins with the virus attaching to its host cell. It continues with injection of viral genes into the cell.
[!!!!] +++card 24+++ [/!!!]
[q]The lytic cycle begins with the virus attaching to its host cell. It continues with injection of viral _____ into the cell.
[textentry]
[a]The lytic cycle begins with the virus attaching to its host cell. It continues with injection of viral genes into the cell.
[!!!!] +++card 26+++ [/!!!]
[q]The lytic cycle ends with lysis: the _____ apart of the host cell as viral progeny are released.
[textentry]
[a]The lytic cycle ends with lysis: the bursting apart of the host cell as viral progeny are released.
[!!!!] +++card 28+++ [/!!!]
[q]In the _____ cycle, viral genes are incorporated into the host cell’s chromosomes.
[textentry]
[a]In the lysogenic cycle, viral genes are incorporated into the host cell’s chromosomes.
[!!!!] +++card 30+++ [/!!!]
[q]In the lysogenic cycle, viral genes are incorporated into the host cell’s _____.
[textentry]
[a]In the lysogenic cycle, viral genes are incorporated into the host cell’s chromosomes.
[!!!!] +++card 32+++ [/!!!]
[q]In viruses that attack bacteria, the viral genes that have _____ themselves into the host’s chromosome are known as a prophage.
[textentry]
[a]In viruses that attack bacteria, the viral genes that have integrated themselves into the host’s chromosome are known as a prophage.
[!!!!] +++card 34+++ [/!!!]
[q]In viruses that attack _____, the viral genes that have integrated themselves into the host’s chromosome are known as a provirus.
[textentry]
[a]In viruses that attack eukaryotes, the viral genes that have integrated themselves into the host’s chromosome are known as a provirus.
[!!!!] +++card 36+++ [/!!!]
[q]In viruses that attack eukaryotes, the viral genes that have integrated themselves into the host’s chromosome are known as a _____.
[textentry]
[a]In viruses that attack eukaryotes, the viral genes that have integrated themselves into the host’s chromosome are known as a provirus.
[!!!!] +++card 38+++ [/!!!]
[q]HIV causes _____.
[textentry]
[a]HIV causes immunodeficiency.
[!!!!] +++card 40+++ [/!!!]
[q]Immunodeficiency raises an individual’s vulnerability to _____ and infection.
[textentry]
[a]Immunodeficiency raises an individual’s vulnerability to cancer and infection.
[!!!!] +++card 42+++ [/!!!]
[q]HIV’s genes are made of _____.
[textentry]
[a]HIV’s genes are made of RNA.
[!!!!] +++card 44+++ [/!!!]
[q]Outside HIV’s capsid is a phospholipid membrane, derived from its last _____.
[textentry]
[a]Outside HIV’s capsid is a phospholipid membrane, derived from its last victim.
[!!!!] +++card 46+++ [/!!!]
[q]HIV binds with a membrane protein called _____.
[textentry]
[a]HIV binds with a membrane protein called CD4.
[!!!!] +++card 48+++ [/!!!]
[q]Binding with CD4 causes a T cell’s membrane to _____ and allow in HIV’s enzymes and genes.
[textentry]
[a]Binding with CD4 causes a T cell’s membrane to open and allow in HIV’s enzymes and genes.
[!!!!] +++card 50+++ [/!!!]
[q]Binding with CD4 causes a T cell’s membrane to open and allow in HIV’s enzymes and _____.
[textentry]
[a]Binding with CD4 causes a T cell’s membrane to open and allow in HIV’s enzymes and genes.
[!!!!] +++card 52+++ [/!!!]
[q]The enzyme reverse transcriptase transcribes HIV’s _____ into DNA. That makes HIV a retrovirus.
[textentry]
[a]The enzyme reverse transcriptase transcribes HIV’s RNA into DNA. That makes HIV a retrovirus.
[!!!!] +++card 54+++ [/!!!]
[q]The enzyme reverse transcriptase transcribes HIV’s RNA into DNA. That makes HIV a _____.
[textentry]
[a]The enzyme reverse transcriptase transcribes HIV’s RNA into DNA. That makes HIV a retrovirus.
[!!!!] +++card 56+++ [/!!!]
[q]After being converted into DNA, HIV’s genes integrate themselves into the T cell’s _____.
[textentry]
[a]After being converted into DNA, HIV’s genes integrate themselves into the T cell’s chromosomes.
[/qdeck]